Sailing between Scylla and Charybdis: Mayelane v Ngwenyama H

Between Scylla and Charybdis.

The ethical dilemmas of treating fulminant (or subfulminant) hepatic failure with liver replacement have been apparent since the earliest trials of this procedure. Acute hepatic failure was the indication for orthotopic liver transplantation in only I of our first 237 recipients I and accounted for only 8 of the next 300.2 Our reluctance to proceed with more cases was that unlike candidates who...

Statin-induced insulin resistance through inflammasome activation: sailing between Scylla and Charybdis.

Elevated LDL cholesterol is an independent risk factor for cardiovascular disease (CVD), and current clinical guidelines recommend aggressive reduction as the preferred course of treatment (1). Type 2 diabetes (T2D) also is a major and independent risk factor for development of CVD (2). A plethora of clinical data exists substantiating the beneficial effects of treatment with inhibitors of 3hyd...

Psychiatric paternalism between Scylla and Charybdis

As much as strong medical paternalism should never be exercised, some weak paternalism towards patients is, on the contrary, part of physicians' and society's moral obligation. So far, this is a widely consented position in medical ethics. What then are the defining and the justifying conditions for legitimate weak paternalism in psychiatry? In this presentation it is argued in favor of three n...

Delphi: Somewhere between Scylla and Charybdis?

N-acetylcysteine somewhere between Scylla and Charybdis.

hiele et al. (1) report a study dealing with the impact of -acetylcysteine (NAC) administered simultaneously on preventng iodinated contrast agent-induced nephropathy and reperfusion njury in patients with ST-segment elevation myocardial infarction reated by percutaneous coronary intervention (PCI). The study ncluded 126 patients compared with a placebo-treated group. heir results as well as co...